Animal-model concordance

Study

Pan-glioma analyses reveal species- and tumor-specific regulation of neuron-glioma synapse genes by lncRNAs

2023 · primary-comparison · peer reviewed: yes · record 37693314 · PubMed

3 findings kept from this study. Each is one sentence comparing an animal with a human, extracted from the full text, checked against the located page, and adjudicated against the review's definition of an animal-versus-human comparison.

NGS genes in mouse PDX models showed similar expression levels to NGS genes in human MB.

Concordant · level A · mouse · oncology

“Fourth, NGS genes in mouse MB PDX showed similar expression levels to NGS genes in human MB”
page 8

NGS genes in mouse transgenic MB showed different expression levels from NGS genes in human GBM.

Discordant · level A · mouse · oncology

“NGS genes in mouse transgenic MB showed different expression levels from NGS genes in human GBM (Supplementary Table S6).”
page 8

LINC00461 regulates NGS genes in mouse MB PDX but does not regulate any NGS gene in human gliomas.

Discordant · level A · mouse · oncology

“We found that LINC00461 regulates NGS genes in mouse MB PDX but does not regulate any NGS gene in human gliomas.”
page 8

Full texts are copyrighted and are not republished here. The quote is the evidence for the extracted value, and the page number lets you check it in the original.