Animal-model concordance

Study

Amphetamine increases motivation of humans and mice as measured by breakpoint, but does not affect an Electroencephalographic biomarker

2024 · primary-comparison · peer reviewed: yes · record 38168850 · PubMed

1 finding kept from this study. Each is one sentence comparing an animal with a human, extracted from the full text, checked against the located page, and adjudicated against the review's definition of an animal-versus-human comparison.

Amphetamine increased breakpoint in mice (cohort 2, without EEG tethering) at 0.3 mg/kg.

Concordant · level A · mouse · neurology

“In cohort 2, however, 0.3 mg/kg of amphetamine increased breakpoint consistent with human findings.”
page 1

Full texts are copyrighted and are not republished here. The quote is the evidence for the extracted value, and the page number lets you check it in the original.