Study

From signal to significance: characterizing anthracycline-related hypercoagulable adverse events via pharmacovigilance, animal models, and clinical observation

2026 · primary-comparison · peer reviewed: yes · record 42602169 · PubMed

1 finding kept from this study. Each is one sentence comparing an animal with a human, extracted from the full text, checked against the located page, and adjudicated against the review's definition of an animal-versus-human comparison.

The paper found that pathways related to cyclic adenosine monophosphate (cAMP) signaling and heparan sulfate biosynthesis were directionally consistent between experimental models and clinical samples.

Concordant · level C · no species named · oncology

“Exploratory analyses suggested potential involvement of pathways related to cyclic adenosine monophosphate (cAMP) signaling and heparan sulfate biosynthesis, which were directionally consistent with observed alterations in coagulation-related parameters in clinical samples and experimental models.”
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